2012 - Pharmacist Digest

How Seth Rogen and Lauren Miller Rogen are using comedy to support Alzheimer’s care

STAT

SEPTEMBER 8, 2023

Since 2012, comedian and filmmaker Lauren Miller Rogen and her husband, actor and comedian Seth Rogen, have used humor to help raise awareness for Alzheimer’s disease and funds for at-home caregiving through their nonprofit Hilarity for Charity. Alzheimer’s isn’t funny.

Decline in heart failure deaths has been undone, led by people under 45

STAT

APRIL 24, 2024

death certificate data from 1999 through 2021, revealing a steady drop in deaths until 2012, when rates plateaued, then began to rise steadily, and accelerated upward once the Covid-19 pandemic arrived. The concerning conclusion comes as newer medications are raising hopes for better outcomes in the years to come.

Congenital syphilis cases in the U.S. have skyrocketed, CDC says

STAT

NOVEMBER 7, 2023

The number of cases of congenital syphilis in 2022 was more than 10 times the number recorded in 2012, the agency said, noting that most of the 3,761 cases reported in 2022 could have been averted, if the babies’ mothers had been adequately tested and treated. Read the rest…

Brain worms are more common than you think. Here’s what doctors who’ve treated them say.

STAT

MAY 8, 2024

was mistakenly diagnosed with a brain tumor after scans picked up abnormalities that turned out to be “caused by a worm that got into my brain and ate a portion of it and then died,” he reportedly said in a 2012 deposition reviewed by The New York Times. Kennedy Jr. Read the rest…

Opinion: The rare pediatric disease voucher program creates new treatments. I have new data to prove it

STAT

JULY 2, 2024

The Food and Drug Administration’s rare pediatric disease priority review voucher program , which has been providing incentives for lifesaving innovations since 2012, is doomed to disappear unless Congress reauthorizes it before the end of September. I have data showing it works.

Labelling

The story of the giraffe, its neck, and a possible treatment for human heart disease

STAT

AUGUST 16, 2024

Natterson-Horowitz is a cardiologist, psychiatrist, and evolutionary biologist who co-authored the 2012 book “ Zoobiquity: The Astonishing Connection Between Human and Animal Health.”

Intermittent fasting for teens? Obesity study finds benefits but only under careful supervision

STAT

SEPTEMBER 20, 2024

In 2012, British journalist Michael Mosley sparked a global trend with his BBC documentary, “Eat, Fast and Live Longer.” ” Seeking a simple way to get healthy without growing his to-do list, Mosley discovered fasting. It’s all a matter of what you eat.

The story of the giraffe, its neck, and a possible treatment for human heart disease

STAT

AUGUST 16, 2024

Natterson-Horowitz is a cardiologist, psychiatrist, and evolutionary biologist who co-authored the 2012 book “ Zoobiquity: The Astonishing Connection Between Human and Animal Health.”

Opinion: Journals that published Richard Lynn’s racist ‘research’ articles should retract them

STAT

JUNE 20, 2024

In 2012, the Elsevier journal Personality and Individual Differences published a special issue that included articles with titles like “Life history theory and race differences: An appreciation of Richard Lynn’s contribution to science” and “National IQs and economic outcomes.”

New analysis reveals postpartum sterilization rates are higher among U.S. women with sickle cell

STAT

OCTOBER 1, 2024

Performed by researchers at Johns Hopkins University, the study found that between 2012 and 2019, 8.8% . Now, a data analysis commissioned by STAT shows that the rate of postpartum sterilization is significantly higher in Americans with sickle cell disease than in those without. of births to unaffected mothers did.

STAT+: CRISPR’s pioneers reflect on the first gene-editing treatment

STAT

NOVEMBER 18, 2023

Jennifer Doudna and Emmanuelle Charpentier, now Nobelists , published their first paper announcing a new enzyme for editing DNA in Science in June 2012. The revolution started in silence. It was called CRISPR-Cas9.

How an ER doctor in Chicago is tackling trauma from gun violence

STAT

OCTOBER 20, 2023

He saw his brother excel at what he did, but Pratt’s life changed in 2012 when his brother was shot and killed in Chicago’s South Side. Abdullah Pratt was only ever interested in science and in sports because of his older brother Rashad.

Why doesn’t the U.S. have more Black midwives?

STAT

SEPTEMBER 18, 2023

more than doubled from 1991 and 2012 and has continued to grow steadily in the years since. The number of credentialed midwives — including both certified nurse-midwives, who can attend births in hospital settings, and a minority of certified midwives, who don’t hold a nursing degree — in the U.S.

Hospitals

STAT+: Regeneron accused by Justice Department of manipulating Medicare pricing

STAT

APRIL 10, 2024

From 2012 to 2021, Regeneron’s credit card fee reimbursements for Eylea purchases exceeded $250 million to just one of its several distributors. Continue to STAT+ to read the full story…

Drug Pricing

STAT+: These 10 scientists are leading a new generation of gene editors developing CRISPR medicines

STAT

OCTOBER 31, 2024

There’s Jennifer Doudna and Emmanuelle Charpentier, the Nobel-prize winning authors of a 2012 Science paper that detailed how CRISPR-Cas9 worked in bacterial cells. If you’ve been following the biomedical revolution now thoroughly underway, then you likely know the names of the scientific luminaries who kicked it all off.

STAT+: Endo Health ordered to pay more than $1.5 billion in opioid criminal case

STAT

MAY 7, 2024

The company, which last month pleaded guilty to a misdemeanor, admitted that, from April 2012 through May 2013, some of its sales representatives marketed its medicine, also known as oxymorphone, to doctors by touting the drug as abuse deterrent, as well as resistant to tampering and crushing.

Pharmaceutical Companies

Pharmaceutical Companies Pharmaceutical Companies

Routine screening for kidney disease would be cost-effective, study argues

STAT

MAY 22, 2023

In 2012, the United States Preventive Services Task Force convened to determine whether it should recommend kidney disease screening for all Americans. Advocates had been pushing for it, citing ballooning rates of chronic kidney disease. But at the time, the group found there wasn’t enough evidence to say if screening was a net good.

A new study shows how Medicaid coverage policies shape maternal health disparities

STAT

JULY 18, 2023

But many immigrants don’t have access to this coverage, making them more vulnerable to maternal health problems, as highlighted by a new study of nearly 73,000 postpartum people across 19 states and New York City between 2012 and 2019. Read the rest…

STAT+: They were the 10% left out of life-changing treatments. Now these cystic fibrosis patients may finally get help

STAT

FEBRUARY 3, 2023

The drugs, a number of so-called modulators approved starting in 2012, have been one of the great biotech success stories. Continue to STAT+ to read the full story…

Drug Development

STAT+: NIH grant recipients often fail to disclose agency support in patent applications

STAT

MAY 4, 2023

Between 2012 and 2021, 14% of roughly 19,000 patent applications did not disclose financial support from the NIH or did not do so as required by federal law. And a new analysis finds a key reason may be most institutions and researchers that receive NIH support fail to fully or correctly disclose this information when applying for patents.

Drug Development

Drug Development Drug Pricing

STAT+: Former FDA official lays out how to keep patients safe from risky medical devices

STAT

OCTOBER 2, 2023

” That train of thought — calculating risks, eliminating threats — eventually led her to a job with the Food and Drug Administration in 2012 as a public health analyst. And I thought, doesn’t that mean nobody should really be sliding down poles?”

Hospitals

New CDC opioid guidelines emphasize flexibility in treating pain

STAT

NOVEMBER 3, 2022

The original guidelines , issued in 2016, helped further drive down opioid prescribing levels that had been in decline since 2012, as the country grappled with its legacy of overprescribing that contributed to the overdose epidemic.

STAT+: What FDA mandate? Sun Pharma halts shipments from a plant with a troubled history

STAT

MAY 9, 2023

In 2012, Ranbaxy paid a $350 million fine to U.S. As a result, the company has halted exports from the plant to the United States. At issue is a facility Sun bought eight years ago from Ranbaxy Laboratories, which was a poster child for lax manufacturing standards in India.

STAT+: ‘It’s like Groundhog Day’: The cancer drug shortage isn’t new — and neither are the solutions

STAT

JUNE 28, 2023

He saw her over a decade ago, when the country was facing a different methotrexate shortage back in 2012. But Unguru didn’t see this particular patient recently or even in the last year. Continue to STAT+ to read the full story…

Chemotherapy

Chemotherapy Hospitals Drug Pricing

EC grants orphan drug designation for Precigen’s PRGN-2012

Pharmaceutical Technology

JANUARY 17, 2024

The EC has granted orphan drug designation (ODD) for Precigen's PRGN-2012 aimed at treating recurrent respiratory papillomatosis (RRP).

America’s ERs struggle with timely care for stroke patients

STAT

AUGUST 15, 2023

One study found that, of nearly 40,000 patients who received a surgery to treat ischemic stroke from 2012 to 2017, close to half required inter-hospital transfer.

Hospitals

STAT+: Pharmalittle: We’re reading about AstraZeneca’s CEO pay, an ALS drug spat in the U.K., and more

STAT

APRIL 1, 2024

Since taking the helm in 2012, Soriot has turned AstraZeneca into the second-largest company on the FTSE 100 index and last year received £16.9 … AstraZeneca’s plan to pay chief executive officer Pascal Soriot up to £18.7 and European peers.

Opinion: STAT+: An overlooked way to make participants in clinical trials look more like America

STAT

MAY 26, 2023

From 2012-2018, for example, Hispanic people comprised just 9% of participants in NIH-funded studies yet make up approximately 20% of the U.S. population. Continue to STAT+ to read the full story…

Opinion: STAT+: What Mark Cuban gets wrong about prescription drugs

STAT

AUGUST 10, 2023

trillion from 2012 to 2021, according to the Association for Accessible Medicines, a trade group representing generic drug manufacturers. That’s 23 percent more than the country’s overall inflation rate during the same period. Meanwhile, generic drug companies saved the U.S. roughly $2.6

Pharmaceutical Companies

Pharmaceutical Companies Pharmaceutical Companies

UK biotech sees worst funding downturn since 2012

pharmaphorum

JANUARY 27, 2023

Indeed, Initial Public Offerings (IPOs) raised just £28 million – the worst annual haul since 2012 – and, during the entirety of last year, UK biotech raised just £1.8 The post UK biotech sees worst funding downturn since 2012 appeared first on. billion, way down from £4.5 billion in 2021. billion raised.

Compounding

Compounding Pharmaceutical Companies Pharmaceutical Companies

FDA is taking on tampons and ‘misleading’ ads starring Serena Williams

STAT

SEPTEMBER 12, 2024

Designed in 2012 to encourage drug development for rare childhood diseases, the program provides vouchers to groups who get a drug in that area approved. A lifeline or a pharma handout? Either way, this program is set to expire There’s an obscure U.S. government voucher program due to sunset at the end of this month.

Drug Development

Diversity in clinical trials has actually dropped since 2012, IQVIA finds

Outsourcing Pharma

MARCH 20, 2023

Despite diversity being spoken about more than ever before, research discovers clinical trials are less representative of the US population compared to a decade prior.

Understanding the Patent Trial and Appeal Board (PTAB) – A Comprehensive Overview

Drug Patent Watch

JULY 21, 2024

The Patent Trial and Appeal Board (PTAB) is a crucial component of the United States Patent and Trademark Office (USPTO), established in 2012 by the Leahy-Smith America Invents Act (AIA).

SAEM Clinical Images Series: A Dangerous Cause of Abdominal Pain

ALiEM - Pharm Pearls

SEPTEMBER 1, 2023

2012 Oct;55(7):930-9. Epub 2012 Jun 19. Cheng NC, Yu YC, Tai HC, Hsueh PR, Chang SC, Lai SY, Yi WC, Fang CT. Recent trend of necrotizing fasciitis in Taiwan: focus on monomicrobial Klebsiella pneumoniae necrotizing fasciitis. Clin Infect Dis. doi: 10.1093/cid/cis565. PMID: 22715175.

Diabetes

Diabetes Hospitals

When £17m isn’t enough: FTSE firms plead to pay bosses millions more

The Guardian - Pharmaceutical Industry

MARCH 10, 2024

The latest award brings to £137m the amount he has earned since joining in 2012. a year earlier. While it drew the anger of corporate governance experts, Soriot’s generous payout was just a fraction of the sums his counterparts at the biggest US companies take home.

Packaging

STAT+: Pharmalittle: Biotech investors push to extend time before Medicare price negotiations; RiteAid closings could cause pharmacy deserts

STAT

OCTOBER 18, 2023

since 2012, and coverage of it has continued to rise in recent years — 36% of those who could benefit from PrEP were prescribed it last year. Expanding PrEP use is a key part of a CDC program to end the HIV epidemic in the U.S. and reduce HIV infections in the country by 90% by 2030. PrEP has been available in the U.S.

Drug Pricing

Climate change likely to bring mosquito-borne diseases to UK, UKHSA warns

The Pharmacist

DECEMBER 11, 2023

These are stark warnings featured in today’s UKHSA report on the effects of climate change – the first of its kind since 2012. Heat-related deaths are estimated to increase by one and a half times in the 2030s, while mosquito-borne diseases are also likely to come to the UK in the ‘near future’.

Vaccines

340B program continues to drive shift in care to more expensive hospital settings

PhRMA

DECEMBER 15, 2022

In this case, the Berkeley Research Group (BRG) found that nearly 36% of all Medicare Part B therapy sales occurred at 340B hospitals in 2021 , up nearly 17 percentage points since 2012, meaning care is moving from physician offices and non-340B hospitals to 340B hospitals.

Hospitals

Hospitals Physician Offices

SAEM Clinical Images Series: Retrobulbar Spot Sign

ALiEM - Pharm Pearls

JANUARY 29, 2024

2012 Dec;33(7):E263-E267. Epub 2012 Sep 21. The retrobulbar “spot sign” as a discriminator between vasculitic and thrombo-embolic affections of the retinal blood supply. Ultraschall Med. doi: 10.1055/s-0032-1312925. PMID: 23023446. Nedelmann, Matt et al.

AstraZeneca CEO Pascal Soriot’s £17m pay package under fire

The Guardian - Pharmaceutical Industry

FEBRUARY 20, 2024

Soriot, who has made nearly £120m in the decade since he took the helm at the drugmaker in October 2012 , was paid £16.9m last year, including salary, benefits and bonuses, up from £15.3m the year before, according to AstraZeneca’s annual report. Continue reading.

Packaging

SAEM Clinical Images Series: A Lethal Combination of Skin and Lung Findings

ALiEM - Pharm Pearls

JANUARY 8, 2024

2012 Jul;51(7):1278-84. Epub 2012 Feb 29. The diagnostic utility of anti-melanoma differentiation-associated gene 5 antibody testing for predicting the prognosis of Japanese patients with DM. Rheumatology (Oxford). doi: 10.1093/rheumatology/ker518. PMID: 22378718. Moghadam-Kia S, Oddis CV, Sato S, Kuwana M, Aggarwal R.

Hospitals

Chancellor and former health secretary protests local pharmacy closure

The Pharmacist

AUGUST 15, 2023

Mr Hunt, who was the Secretary of State for Health and Social Care between 2012 and 2018, has added his name to two local petitions against the potential closure of a Boots pharmacy […] The post Chancellor and former health secretary protests local pharmacy closure appeared first on The Pharmacist.

Episode 908: Finally, All the VTE Recommendations In One Document!

Pharmacy Joe

MARCH 27, 2024

This meant that any unchanged guidance statements from the 2012 9th edition were still considered to be part of the guidelines, but were not reprinted in the 2016 document. These 5 statements and their rationale for deletion are as follows: From 2012: Statement 2.5.2

Documentation

Documentation Inpatient

SAEM Clinical Images Series: When Needles Go Beyond Sewing and Acupuncture

ALiEM - Pharm Pearls

OCTOBER 25, 2024

Epub 2012 Nov 30. Lane JC, Mabvuure NT, Hindocha S, Khan W. Current concepts of prophylactic antibiotics in trauma: a review. Open Orthop J. 2012;6:511-7. doi: 10.2174/1874325001206010511. PMID: 23248721; PMCID: PMC3522105.

Vaccines

Vaccines Immunity Immunization

How Seth Rogen and Lauren Miller Rogen are using comedy to support Alzheimer’s care

Decline in heart failure deaths has been undone, led by people under 45

Trending Sources

Congenital syphilis cases in the U.S. have skyrocketed, CDC says

Brain worms are more common than you think. Here’s what doctors who’ve treated them say.

Opinion: The rare pediatric disease voucher program creates new treatments. I have new data to prove it

The story of the giraffe, its neck, and a possible treatment for human heart disease

Intermittent fasting for teens? Obesity study finds benefits but only under careful supervision

The story of the giraffe, its neck, and a possible treatment for human heart disease

Opinion: Journals that published Richard Lynn’s racist ‘research’ articles should retract them

New analysis reveals postpartum sterilization rates are higher among U.S. women with sickle cell

STAT+: CRISPR’s pioneers reflect on the first gene-editing treatment

How an ER doctor in Chicago is tackling trauma from gun violence

Why doesn’t the U.S. have more Black midwives?

STAT+: Regeneron accused by Justice Department of manipulating Medicare pricing

STAT+: These 10 scientists are leading a new generation of gene editors developing CRISPR medicines

STAT+: Endo Health ordered to pay more than $1.5 billion in opioid criminal case

Routine screening for kidney disease would be cost-effective, study argues

A new study shows how Medicaid coverage policies shape maternal health disparities

STAT+: They were the 10% left out of life-changing treatments. Now these cystic fibrosis patients may finally get help

STAT+: NIH grant recipients often fail to disclose agency support in patent applications

STAT+: Former FDA official lays out how to keep patients safe from risky medical devices

New CDC opioid guidelines emphasize flexibility in treating pain

STAT+: What FDA mandate? Sun Pharma halts shipments from a plant with a troubled history

STAT+: ‘It’s like Groundhog Day’: The cancer drug shortage isn’t new — and neither are the solutions

EC grants orphan drug designation for Precigen’s PRGN-2012

America’s ERs struggle with timely care for stroke patients

STAT+: Pharmalittle: We’re reading about AstraZeneca’s CEO pay, an ALS drug spat in the U.K., and more

Opinion: STAT+: An overlooked way to make participants in clinical trials look more like America

Opinion: STAT+: What Mark Cuban gets wrong about prescription drugs

UK biotech sees worst funding downturn since 2012

FDA is taking on tampons and ‘misleading’ ads starring Serena Williams

Diversity in clinical trials has actually dropped since 2012, IQVIA finds

Understanding the Patent Trial and Appeal Board (PTAB) – A Comprehensive Overview

SAEM Clinical Images Series: A Dangerous Cause of Abdominal Pain

When £17m isn’t enough: FTSE firms plead to pay bosses millions more

STAT+: Pharmalittle: Biotech investors push to extend time before Medicare price negotiations; RiteAid closings could cause pharmacy deserts

Climate change likely to bring mosquito-borne diseases to UK, UKHSA warns

340B program continues to drive shift in care to more expensive hospital settings

SAEM Clinical Images Series: Retrobulbar Spot Sign

AstraZeneca CEO Pascal Soriot’s £17m pay package under fire

SAEM Clinical Images Series: A Lethal Combination of Skin and Lung Findings

Chancellor and former health secretary protests local pharmacy closure

Episode 908: Finally, All the VTE Recommendations In One Document!

SAEM Clinical Images Series: When Needles Go Beyond Sewing and Acupuncture

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