European Pharmaceutical Review

JANUARY 29, 2024

22,23 Dissolution In EPR Issue 4 2023 the “key role that dissolution testing has in the quality control of pharmaceutical drug products, its relevance for poorly soluble compounds, and how its limitations can impact determination of bioavailability” 24 was examined. 2011 Dec;12(4):1248-63. 2011; 8(4): 330-345. AAPS PharmSciTech.

Drug Development 111

Drug Development Vaccines Compounding 111

RX Note

JANUARY 21, 2023

Adverse Drug Reaction Drug Induced Diseases, 2018 Meyler's Side Effects of Drugs, 2015 Antibiotics The Sanford Guide to Antimicrobial Therapy, 2022 Breastfeeding Briggs' Drugs in Pregnancy and Lactation, 2021 Hale's Medications and Mothers' Milk, 2021 Clinical Practice Applied Therapeutics, 2018 Conn’s Current Therapy, 2022 Current Medical Diagnosis (..)

Compounding 40

Compounding Community Pharmacies Clinical Pharmacology Dosage 40

pharmaphorum

APRIL 10, 2022

10,808,039) covering ADCs that include auristatin compounds coupled to an antibody via a linker molecule. Seagen has a long history in ADC development, claiming FDA approval for Adcetris (brentuximab vedotin) as a treatment for classical Hodgkin lymphoma and anaplastic large cell lymphoma (ALCL) in 2011.

Compounding 52

Compounding 52

pharmaphorum

FEBRUARY 15, 2022

Lilly originally agreed paid $20 million upfront for a license to the maytansinoid technology in 2011, and expanded the partnership two years later, only to exit the agreement in 2018.

Compounding 52

Compounding 52

European Pharmaceutical Review

JULY 4, 2024

Herbal medicines placed on the market since April 2011 must have either a traditional herbal registration (THR) or a Marketing Authorisation (MA). The intricate nature of botanical products further compounds the challenge, demanding a paradigm shift in regulatory interpretation and QC standards. 2012/1916).

Drug Development 103

Drug Development Biosimilars Documentation Labelling 103

European Pharmaceutical Review

APRIL 8, 2024

stated that when conventional small-molecule compounds were the norm within the industry, closed innovation was standard practise and pharmaceutical companies did R&D in-house. Yet from 2011, these arrangements were the subject of “patent-non- exclusive rights, technology- exclusive rights and technology-supply”. Yoshiura et al.

Pharmaceutical Companies 52

Pharmaceutical Companies Pharmaceutical Companies Compounding 52

The Thyroid Pharmacist

AUGUST 18, 2023

Benefits and Uses of Curcumin Turmeric’s medicinal benefits can mostly be attributed to compounds called curcuminoids. Combining curcumin with piperine, an alkaloid found in black pepper, extends the life of curcumin in the body, making its compounds more therapeutically effective. Curcumin is the active component in turmeric.

Dosage 98

Dosage Compounding Labelling Diabetes 98

RX Note

JUNE 5, 2023

Phenylketonuria Risk Aspartame is catabolized to phenylalanine among other compounds, making it unsafe for consumption in individuals with phenylketonuria. Stability at High Temperature Aspartame is unstable at high temperatures and cannot be used for baking or cooking.

Packaging 52

Packaging Compounding Diabetes 52

FDA Law Blog: Biosimilars

DECEMBER 3, 2023

As part of this change, the Coverage Gap Discount Program (CGDP), a program that has existed since 2011, will sunset on December 31, 2024, and be replaced by the Medicare Part D Manufacturer Discount Program (the “Discount Program”). Kirschenbaum — The Inflation Reduction Act (IRA) significantly changed the Part D benefit.

Labelling 105

Labelling Drug Pricing Compounding Payment Processing 105

The Thyroid Pharmacist

SEPTEMBER 2, 2022

Milk Thistle: Silymarin (one of the compounds in milk thistle) may be therapeutic in metabolic syndrome (insulin resistance syndrome) in its potential to improve insulin sensitivity and decrease blood sugar. Smart Publications, 2011. 2011 Dec;16(6):482. 2011 Dec;34(12):2551-4. Epub 2011 Oct 12. Epub 2011 Oct 12.

Diabetes 98

Diabetes Health and Personal Care Stores Immunity Immunization 98

Ramblings of a pharmacist

FEBRUARY 16, 2022

For example, “In the compounding period of 1941, the average pharmacy filled about 5,000 prescriptions a year, approximately 15 a day.” In both his 2011 article and his article from yesterday, he makes the same point “pharmacy gross profits remain stable,” - but the figure in 2009 was 23.8%

Independent Pharmacies 52

Independent Pharmacies Compounding Specialty Pharmacies Prescription Filling 52

RX Note

AUGUST 4, 2023

Apart from Malaysian Clinical Practice Guidelines , other recommended local references include: ADR Reporters Guide Ampang Protocol, 2012 Anticoagulation MTAC Protocol, 2020 Antidote Quick Guide, 2022 Cancer Drug Counselling A Guide for Pharmacist, 2017 Clinical Pharmacokinetics Pharmacy Handbook, 2019 Code of Ethics for Pharmacists, 2018 Critical (..)

Hospitals 52

Hospitals Inpatient Community Pharmacies Dosage 52

Pharmaceutical Technology

MAY 11, 2008

For example, Turkey will require track and trace by 1 January 2009 and California is requiring the technology by 1 January 2011. ” Laser marking solution company Datalase has developed a system where an inactive compound can be added to the tablet formulation.

Packaging 40

Packaging Labelling Pharmaceutical Companies Pharmaceutical Companies 40

The Thyroid Pharmacist

JULY 29, 2022

I’ve seen a number of airborne toxins showing up as frequent triggers/exacerbating factors for my clients’ autoimmune conditions — mold, volatile organic compounds (VOCs), and artificial/synthetic fragrances, in particular. For cleaning products, only compounds need to be identified. Volatile Organic Compounds (VOCs) .

Health and Personal Care Stores 52

Health and Personal Care Stores Compounding Immunization Immunity 52

The Thyroid Pharmacist

DECEMBER 6, 2023

22] Nightshades contain alkaloids, which are chemical compounds that can be reactive substances in some people. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. [15] Forty-seven percent of readers found removing nightshades relieved their joint aches, pain, swelling, tingling, and numbness. In: Benzie IFF, Wachtel-Galor S, eds.

Immunization 98

Immunization Immunity Adverse Reactions Packaging 98

GMPSOP

JUNE 9, 2024

FDA – Process Validation Guidelines (published in January 2011) are crucial for maintaining the quality management system. assay result) meeting its predetermined specifications and quality attributes (i.e., accuracy, precision, etc.) Reagents should only be used for the purposes for which they were designed.

Method Validation 52

Method Validation Documentation Health and Personal Care Stores Labelling 52

The Thyroid Pharmacist

NOVEMBER 3, 2023

9] When the body is exposed to an allergen, histamine production increases and turns on inflammatory processes to protect the body from that compound. 2011 Dec;62(6):591-9. 8] Histamine intolerance: Histamine is a chemical that is produced as part of our immune response to a sensitivity or inflammatory reaction. [9] PMID: 22314561. [54]

Immunity 98

Immunity Immunization Dosage Mayo Clinic 98

The Thyroid Pharmacist

AUGUST 19, 2022

Thymoquinone (TQ), one of the active compounds found in black seed oil, acts as a biofilm disruptor, meaning that it can break free from the protective coating that H. 38) The antibacterial properties of black seed oil may play a role in the treatment of H. pylori uses to protect itself, allowing antibacterial components to reach the H.

Health and Personal Care Stores 98

Health and Personal Care Stores Immunization Immunity Dosage 98

The Thyroid Pharmacist

DECEMBER 7, 2022

A few of the most common types of flame retardants include: Halogenated compounds (containing bromine and/or chlorine and known as polychlorinated biphenyls, polybrominated diphenyl ethers, etc.). 2011 Jan;119(1):A11. Published May 2011. Published May 2011. Endocr Connect. 2018;7(4):R160-R186. [2] Environ Health Perspect.

Health and Personal Care Stores 77

Health and Personal Care Stores Labelling Immunization Immunity 77

The Thyroid Pharmacist

OCTOBER 7, 2022

Stevia is a natural sweetener derived from the plant Stevia rebaudiana , or “honey leaf,” which contains the sweet-tasting compounds known as steviol glycosides. It was also introduced as a sweetener in the EU in 2011, as well as in Canada in 2012. Stevioside and related compounds: therapeutic benefits beyond sweetness.

Diabetes 98

Diabetes Immunization Immunity Labelling 98

The Thyroid Pharmacist

SEPTEMBER 1, 2023

The fluorine anion (negatively charged ion), or any of the compounds containing the anion, are termed fluorides. The fluoride in drinking water comes from the addition of a fluorine compound (usually sodium fluoride, sodium fluorosilicate, or fluorosilicic acid), which dissociates to release the F- ion.

Adverse Reactions 116

Adverse Reactions Compounding Chemotherapy Labelling 116

The Thyroid Pharmacist

JANUARY 6, 2023

From 2008 to 2011, the majority of my recommendations as a consultant pharmacist were to reduce or taper antipsychotic medications for clients due to the horrible side effects and lack of perceived benefit. Taking a T3-containing medication, in particular, has been shown to reduce symptoms of depression.

Dosage 122

Dosage Labelling Communication Compounding 122

The Thyroid Pharmacist

MAY 19, 2023

20] This medication is available only as a prescription and can be compounded into lower doses by special professional compounding pharmacies. doi:10.4061/2011/875125; Ansari MS, Almalki MH. 2011-0228 [10] Dayan C, Panicker V. This means that it turns off the cells that cause autoimmunity! [20] Published 2018 Oct 4.

Immunization 94

Immunization Immunity Diabetes Compounding 94

The Thyroid Pharmacist

MAY 26, 2023

Again, having low stomach acid further compounds this by providing an environment that is not well defended against bacteria. Published August 9, 2011. This condition slows down the normal muscular contractions of the small intestine, which slows down the movement of partially digested food and digestive juices. [13] 2017;15(1):29.

Health and Personal Care Stores 98

Health and Personal Care Stores Diabetes Dosage Immunization 98

The Thyroid Pharmacist

JULY 20, 2023

There are various iron salts, or compounds, and each of them have different levels of elemental iron in them. [63] 79] In a 2011 study, 119 women that had a riboflavin deficiency were given either 2 g or 4 g of riboflavin, or a placebo for eight weeks. [80] 2011 Dec;57(4):369-77. [28] Published 2021 Jan 14. 2020;19(1):32-36.;

Health and Personal Care Stores 93

Health and Personal Care Stores HIV Treatment and Prevention Agents Immunity Immunization 93

The Thyroid Pharmacist

JULY 7, 2023

In a study done in 2010, NAC and 15-Deoxy-Prostaglandin J2 (a fatty acid compound with antioxidant and anti-inflammatory properties) exerted a protective effect against autoimmune thyroid destruction in vivo. [47] 2011-0228 [2] Müssig K, Künle A, Säuberlich AL, et al. 2011-3350 [19] Eschler DC, Hasham A, Tomer Y. doi:10.1210/jc.2011-0228

Immunization 105

Immunization Immunity Diabetes Dosage 105

The Thyroid Pharmacist

JULY 14, 2022

Berberine contains compounds called alkaloids that have broad-spectrum antimicrobial and antiparasitic properties. (33). 2011 Dec;109(6):1745]. I remember speaking to a few doctors who mentioned that berberine seemed to help their Hashimoto’s patients feel better and reduce thyroid antibodies. Southeast Asian J Trop Med Public Health.

Mayo Clinic 52

Mayo Clinic Pharmacy Technician Immunity Immunization 52

The Thyroid Pharmacist

JANUARY 20, 2023

Some individuals may be sensitive to anthraquinone compounds, which are present in aloe latex (taken from the outer skin of the plant) and aloe whole leaf extracts. Guduchi has many biologically active compounds viewed as having potential application in clinical research. 2011 May;20(3):225-39. [11] Published 2019 Dec 9.

HIV Treatment and Prevention Agents 98

HIV Treatment and Prevention Agents Diabetes Immunization Immunity 98

The Thyroid Pharmacist

JANUARY 13, 2023

I started talking to Carter Black, RPh, my compounding pharmacist, about the symptoms I was experiencing, and he suggested that I have my adrenals tested. link] Published March 2011. Published 2011 Dec. [18] Future Sci OA. 2015;1(3):FSO23. Published 2015 Nov 1. doi:10.4155/fso.15.21; 15.21; Harvard Health Publishing. 4] Cook SB.

Health and Personal Care Stores 98

Health and Personal Care Stores Diabetes Communication Dosage 98

The Thyroid Pharmacist

NOVEMBER 15, 2024

Compounding pharmacies will sometimes repackage these drugs, or create lower or different concentrations than what’s typically available. Berberine Berberine is a natural compound found in several plants, including goldenseal and barberry. Supports Gut Health Berberine’s alkaloid compounds may help support a balanced gut microbiome.

Diabetes 73

Diabetes Immunization Immunity Compounding 73