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The lingering menace of diethylene glycol / ethylene glycol adulteration

European Pharmaceutical Review

Tamper‑evident packaging is also recommended to prevent adulteration or contamination of the excipient. 24 June 2008. Many excipients are manufactured outside of their major markets, ie, US, Japan and Europe; as such there should be transparency of the supply chain and proper flow of the necessary information.

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Halting Europe’s essential medicines manufacturing exodus

European Pharmaceutical Review

The last paracetamol plant in Europe, closed in France in 2008 as it was no longer economically sustainable, marking the exit of paracetamol manufacturing from Europe” The closure of API manufacturing plants in Europe started in earnest 15 years ago.

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Guido Rasi steps down, handing the running of EMA to Emer Cooke

pharmaphorum

In his final message as head of the EMA, Rasi said the number of COVID-19 drugs and vaccines being developed by pharma companies is “encouraging,” and pointing to the agency’s pivotal role “in reviewing the available data packages to ensure that our usual high standards of safety, efficacy and quality are achieved and upheld.”.

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Extemporaneous Preparation with Unknown Stability

RX Note

Today, stability information can be obtained from manufacturer’s labelling information (such as in the package insert), the USP compounding monographs, or peer-reviewed articles and references , such as articles in American Journal of Health-System Pharmacy, the International Journal of Pharmaceutical Compounding.

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Before & After: Pharmacy’s Digital Revolution

pharmacy mentor

56 UK Online Pharmacies in 2008/9 ( Statista ). Automation , (think Prescription Collection Machines , Dispensing Robots and Packaging Machines) significantly decreases the admin, and therefore long-term expenditure on Rx work. The Digital Revolution in numbers: 721 million UK Prescriptions Dispensed in 2005 (Pharmaceutical Journal).

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Eye Preparations

RX Note

On the other hand, a 2008 study concluded that inadequate refrigeration and prolonged shelf-lives of chloramphenicol generics collected from Delhi and Chennai are associated with very high levels of chloramphenicol thermal breakdown product. In year 2020, there is few interesting findings that I came to realize.

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Thoughts on amendments to ISO 10993-7 medical device ethylene oxide sterilization residuals

Pharmaceutical Technology

In January 2022, the United Kingdom adopted ISO 10993-7:2008 / Amd 1:2019 as BS EN ISO 10993-7:2008 / A1:2022 without modification. It is therefore essential that EO sterilized articles are subjected to sufficient aeration to remove such residues prior to final packaging by manufacturers. Simulated-Use Extraction Procedure.