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The Febrile Infant: Incorporating the 2021 American Academy of Pediatrics guidelines

ALiEM - Pharm Pearls

Children 29 days or older with fever from a documented viral source can be managed according to their clinical presentation and can go outside the algorithm. This requires a documented positive viral swab and not just a presentation consistent with a viral syndrome. 2004 Mar 10;291(10):1261-2. References: Roberts KB.

Hospitals 360
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Trial bias concern scuppers Y-mAbs brain cancer drug in FDA vote

pharmaphorum

The two groups were also separated by a sizeable time difference, with data from the control group ranging between 1990 and 2015, while Study 03-133 started enrolling patients in 2004. Changes in standard and supportive care over the time period could also have skewed the results, said the FDA reviewer.

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Strategies to Overcome Anxiety with Hashimoto’s

The Thyroid Pharmacist

A study in 2004 found an association between the presence of a mood or anxiety disorder, and the presence of anti-TPO antibodies. [1] In the early stages of Hashimoto’s, the thyroid is under attack by the immune system. Thyroid antibodies are a marker that lets us know that the immune system is destroying thyroid tissue.

Immunity 105
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Lasers for Thyroid Tissue Regeneration

The Thyroid Pharmacist

TGF-β modulates inflammation and helps to induce and maintain the “tolerance of self” (which means the immune system is more capable of recognizing itself and less likely to attack itself), thus also reducing thyroid autoimmunity. LLLT also appears to increase Transforming Growth Factor β (TGF-β), which is an anti-inflammatory cytokine.

Dosage 98
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How Thyroid Disease Affects Men

The Thyroid Pharmacist

Both are tied to autoimmune processes in the body, when the immune system begins to recognize different parts of the thyroid gland as foreign invaders. A 2015 case report documented the thyroid labs of a man who had recurrent hyperthyroid episodes after three of his wife’s pregnancies! Published 2004 Aug 18. BMC Psychiatry.