STAT

APRIL 5, 2024

When Francis Collins, then-director of the National Human Genome Research Institute, testified before Congress in 2003 about the significance of sequencing the human genome that year, he introduced personalized medicine as a new concept.

Diabetes 313

Diabetes 313

STAT

MAY 13, 2024

” The answer invariably comes back to a popular 2003 journal article from a quartet of health economists titled, “ It’s The Prices, Stupid.” ” Continue to STAT+ to read the full story…

Hospitals 317

Hospitals 317

STAT

JUNE 21, 2024

Danyel Smith has served 21 years of a life sentence at Dooly Correctional Facility in Unadilla, Georgia, for the 2003 murder of his two-month-old son, Chandler.

Medical Records 350

Medical Records Hospitals 350

STAT

JANUARY 10, 2023

Five studies co-authored by Tessier-Lavigne are now under the microscope for containing alleged altered images: a 1999 Cell study , a 2008 paper in the EMBO Journal, a 2003 Nature study, and two studies published in 2001 in Science.

332

332

STAT

JANUARY 30, 2023

The human genome was sequenced in 2003. The act also created an industry that didn’t exist in the United States before its enactment, enabling the formation of companies to develop and commercialize therapies for rare diseases. That said, a lot has changed in science and drug development since 1983.

Drug Development 252

Drug Development 252

STAT

MARCH 5, 2024

In 2003, the year Nora Volkow was appointed director of the National Institute on Drug Abuse, roughly 4,000 Americans died of opioid overdose. In the two decades since, the overdose crisis has morphed into a full-fledged public health emergency, with 80,000 Americans dying from opioid overdoses each year. treats opioid addiction.

292

292

STAT

JUNE 1, 2023

billion in 2003 to $42.9 But that could end up hammering the NIH budget, which has steadily climbed over the years as Congress channeled billions of dollars to research on cancer, Alzheimer’s disease, and rare diseases. The NIH’s overall budget nearly doubled from $25.8 billion in 2022.

256

256

World Pharma News

SEPTEMBER 20, 2024

It was initially approved by the FDA in 2003 for use in individuals 5 through 49 years of age, and in 2007, the FDA approved the use of FluMist to include children 2 through 5 years of age. FluMist is approved for the prevention of influenza disease caused by influenza virus subtypes A and B in individuals 2 through 49 years of age.

Vaccines 107

Vaccines 107

STAT

MARCH 6, 2023

That was the message Chinese scientists delivered Monday on the opening day of the Third International Summit on Human Genome Editing in London.

246

246

STAT

JANUARY 27, 2023

biomedical research powerhouse, a role he held from 2003 to 2021, when he was appointed to serve as the White House’s first Cabinet-level science adviser to the president. But the founding director will not be back at the helm of the Cambridge, Mass.,

247

247

PharmaShots

APRIL 13, 2023

Through the inclusion of Pharmacia’s products along with a strong performance, Pfizer’s pharmaceutical and animal health revenue was boosted by 40% and 43% respectively In the year 2003, Johnson & Johnson generated a revenue of $41.9B which depicted a growth of 15.3% as compared to the previous year. from last year.

Biosimilars 40

Biosimilars Vaccines Pharmaceutical Companies Pharmaceutical Companies 40

STAT

JULY 5, 2023

Both are run by a husband-and-wife team that has received more than $17 million in NIH funding since 2003, according to the animal rights group. ” The move came more than six months after the People for the Ethical Treatment of Animals notified both the U.S.

Vaccines 245

Vaccines 245

STAT

NOVEMBER 1, 2022

The precedent established in 2003, when the court ruled that race, along with other factors, could be given limited consideration in higher education admissions when necessary to achieve student body diversity, is now in jeopardy.

Medical Schools 258

Medical Schools 258

STAT

NOVEMBER 8, 2022

In 2003, Pancho’s life changed forever. That’s when a car crash sent the 20-year-old farm worker into emergency surgery to repair damage to his stomach. The operation went well, but the next day, a blood clot caused by the procedure cut off oxygen to his brain stem, leaving him paralyzed and unable to speak.

246

246

STAT

APRIL 15, 2024

Advisors, a hedge-fund firm run by brothers Felix and Julian Baker, had in 2003 invested in Seagen, a developer of next-generation cancer treatments. Pfizer bought Baker Bros.  Pfizer bought the company for $43 billion last year.

261

261

Express Pharma

JULY 11, 2024

The group now has 399 approvals and has so far filed over 460 ANDAs (as of March 2024) since the commencement of the filing process in FY 2003-04. Sacubitril and Valsartan tablets had annual sales of USD 5,483 mn in the United States (IQVIA MAT May 2024).

99

99

STAT

SEPTEMBER 22, 2023

Yale and the VA agreed in 2003 to share royalties on patents with inventors from both institutions.  Yale and professor John Krystal agreed to pay $1.5 million to resolve claims that they failed to pay the VA its share of royalties for patents covering intranasal ketamine used to treat depression.

Department of Veterans Affairs 255

Department of Veterans Affairs Pharmacy Technician Compounding Pharmacies Compounding 255

Big Molecule Watch

SEPTEMBER 6, 2024

The PTAB now has granted institution of Sarepta’s IPR, which challenges claims 1, 3-6, and 8 of the ’274 patent as obvious over four prior art references: US 2003/0138772 A1 (“’772 Publication”), Qing Xie et al., 10405–10410 (2002) (“Xie”), Stephen Snowdy, Nuclear targeting by adeno-associated virus capsid proteins and virions (2003) (Ph.D.

62

62

cureatr

AUGUST 10, 2023

Two decades after the Medicare Modernization Act of 2003 created Medicare Part D, nearly 50 million Americans are enrolled in a standalone prescription drug benefit program.

Medication Therapy Management (MTM) 78

Medication Therapy Management (MTM) 78

Pharmacy Times

FEBRUARY 16, 2024

This marks omalizumab’s fourth FDA-approved indication for allergic and inflammatory conditions, such as severe persistent allergic asthma, with its initial approval being in 2003.

57

57

Outsourcing Pharma

JUNE 7, 2021

The US Food and Drug Administration (FDA) has approved Biogenâs Aduhelm (aducanumab) for the treatment of Alzheimerâs: making it the first new treatment approved for the disease since 2003.

98

98

Express Pharma

FEBRUARY 9, 2024

The group now has 387 approvals and has so far filed over 460* ANDAs since the commencement of the filing process in FY 2003-04. Dexamethasone Tablets USP, 1 mg had annual sales of $1.8 million in the United States (IQVIA Dec. The post Zydus gets tentative USFDA approval for Dexamethasone Tablets USP, 1 mg appeared first on Express Pharma.

Immunity 95

Immunity Immunization 95

Express Pharma

APRIL 22, 2024

The group now has 393 approvals and has so far filed over 460* ANDAs since the commencement of the filing process in FY 2003-04. Mirabegron Extended-Release Tablets USP 25mg and 50mg had annual sales of $2.42 billion in the US (IQVIA MAT February 2024). The post Zydus launches Mirabegron ER tablets in US appeared first on Express Pharma.

101

101

Express Pharma

MAY 13, 2024

The group now has 395 approvals and has so far filed over 460 (as of 31st December, 2023) ANDAs since the commencement of the filing process in FY 2003-04. Dexamethasone Tablets USP, 1 mg had annual sales of $ 1.8 million in the United States (IQVIA MAT March 24).

Immunity 71

Immunity Immunization 71

NY Times

JUNE 5, 2021

If the agency approves it, aducanumab would be the first new Alzheimer’s treatment since 2003. Patients are desperate for new options, but some scientists say there isn’t enough evidence it works.

81

81

Orsini Pharmacy

FEBRUARY 27, 2023

In 2003, Tommy was diagnosed with Duchenne Muscular Dystrophy (DMD) , a genetic disorder where the body does not maintain muscle mass due to an inborn lack of the protein dystrophin. On Rare Disease Day, we are dedicating this blog to Tommy, a selfless and caring individual we had the opportunity to serve for several years.

85

85

Express Pharma

FEBRUARY 8, 2024

The group now has 386 approvals and has so far filed over 448* ANDAs since the commencement of the filing process in FY 2003-04. Dexamethasone Tablets USP, 0.5 mg, 4 mg and 6 mg had annual sales of $22 million and Dexamethasone Tablets USP, 2 mg has annual sales of $6 million in the United States (IQVIA Dec.

103

103

Express Pharma

APRIL 19, 2023

The group now has 363 approvals and has so far filed over 440* ANDAs since the commencement of the filing process in FY 2003-04. Roflumilast Tablets, 250 mcg had annual sales of $34 million in the United States (IQVIA MAT Feb. The post Zydus gets USFDA approval for Roflumilast Tablets, 250 mcg appeared first on Express Pharma.

96

96

Express Pharma

OCTOBER 6, 2023

The group now has 381 approvals and has so far filed over 444* ANDAs since the commencement of the filing process in FY 2003-04. Sugammadex Injection, 200 mg/2 mL (100 mg/mL) and 500 mg/5 mL (100 mg/mL), SingleDose Vial had annual sales of $986 million in the United States (IQVIA MAT Aug 2023).

105

105

Pharma Mirror

OCTOBER 4, 2021

In 2003 the Human Genome Project provided the first atlas. Despite untold investment by numerous pharmaceutical companies, FDA-approved drugs that target critical brain functions and conditions like anxiety, depression, and sedation continue to present severe and unpredictable side effects, including suicidal ideation.

Pharmaceutical Companies 119

Pharmaceutical Companies Pharmaceutical Companies 119

The Guardian - Pharmaceutical Industry

SEPTEMBER 9, 2023

Now many believe the money might have been better spent on public health interventions After spending 13 years and $2.7bn, the Human Genome Project announced in 2003 that it had successfully mapped our DNA, paving the way for a new era of medicine that would deliver “the right treatment, for the right patient, at the right time”.

69

69

Express Pharma

NOVEMBER 30, 2023

The group now has 382 approvals and has so far filed over 448* ANDAs since the commencement of the filing process in FY 2003-04. Ivabradine Tablets, 5 mg and 7.5 mg had annual sales of $136.5 million in the United States (IQVIA MAT October,2023). The post Zydus gets US FDA final approval for Ivabradine Tablets, 5 mg and 7.5

101

101

Express Pharma

APRIL 5, 2023

The group now has 358 approvals and has so far filed over 440* ANDAs since the commencement of the filing process in FY 2003-04. Acetazolamide Tablets USP, 125 mg and 250 mg had annual sales of USD 16 mn in the United States (IQVIA MAT Dec.

96

96

Express Pharma

AUGUST 31, 2023

The group now has 378 approvals and has so far filed over 444 ANDAs since the commencement of the filing process in FY 2003-04. Isotretinoin Capsules USP, 10 mg, 20 mg 30 mg and 40 mg had annual sales of $165 million in the United States (IQVIA MAT July 2023).

97

97

Express Pharma

APRIL 6, 2023

The group now has 359 approvals and has so far filed over 440* ANDAs since the commencement of the filing process in FY 2003-04. Carbidopa and Levodopa Tablets USP, 10 mg/100 mg, 25 mg/100 mg, and 25 mg/250 mg had annual sales of $75 million in the United States (IQVIA MAT Dec.

83

83

Express Pharma

APRIL 23, 2023

The group now has 365 approvals and has so far filed over 440* ANDAs since the commencement of the filing process in FY 2003-04. (*as Icosapent Ethyl Capsules, 0.5 g and 1 g had annual sales of $1,316 million in the US (IQVIA MAT Feb. as of 31st December 2022) The post Zydus gets USFDA approval for Icosapent Ethyl Capsules, 0.5

52

52

Big Molecule Watch

FEBRUARY 21, 2024

XOLAIR was initially approved by the FDA in 2003. Food and Drug Administration (FDA) approved XOLAIR (omalizumab) for the reduction of allergic reactions, including anaphylaxis, that may occur with accidental exposure to one or more foods in adult and pediatric patients aged 1 year and older with Immunoglobulin E (IgE)-mediated food allergy.

Biosimilars 57

Biosimilars 57