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Speaking of Medicine – Mid-Year OPDP Enforcement Review

Eye on FDA

By 2002, the number had dropped to 28, reviving somewhat by the end of that decade when it reached 52 in 2010. The characterization of investigative data resulted in a violation related to promotion of an unapproved compound. But when it comes to enforcement things have changed greatly over the years.

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Three strategies for managing loss of exclusivity successfully

pharmaphorum

Eli Lilly’s Humalog compound and formulation patents expired in 2013 and 2014, respectively. 6 The stakes were extremely high, with annual costs of insulin reaching $736 per patient in 2013, up threefold since 2002. RESULT: As of 2002, 40% of PRILOSEC patients had switched to NEXIUM, which notched up sales of $3.9

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Evaluating NMR relaxometry for antibody identification

European Pharmaceutical Review

NMR relaxation methods distinguish between components (phases or compounds) that have different molecular mobilities For monoclonal antibodies, identification methodologies can employ chromatography, spectroscopy, isoelectric focusing, capillary electrophoresis and peptide mapping techniques. 2002; 74(8): 1760–71. Cited 2023Feb].

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From Healing to Harm: The Unintended Consequences of Polypharmacy in Seniors

PharmD Live

The side effects can compound, resulting in a greater negative impact on a patient’s health than the individual effects of one medication alone. New England Journal of Medicine , 365(21), 2002-2012. Adverse Drug Reactions (ADRs) Adverse drug reactions are a major concern in polypharmacy. Lovegrove, M. Campbell, N. Boustani, M.

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A history of Pfizer

pharmaphorum

It was at this time they set their site at Sandwich in the UK, initially just to finish processing compounds imported from America, but due to tariffs on imported products the company rapidly expanded the plant to accommodate producing medicines from scratch. Likewise, tanezumab, an anti-osteoarthritic, failed in trials.

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The Ultimate Guide To Using Enzymes with Hashimoto’s

The Thyroid Pharmacist

Herbal Bitters includes: Ginger : The spicy warmth of ginger comes from gingerol and shogaol, compounds called gingeroids. These compounds are responsible for most of ginger’s beneficial effects on digestion, such as ameliorating occasional indigestion, bloating, belching, and discomfort after meals.

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Solutions for Constipation Relief

The Thyroid Pharmacist

Tegaserod : This medication was approved for IBS-C in 2002, but removed from the market in 2007 due to an increased risk of cardiovascular events. 63] Many of the benefits of ginger are due to gingerol and shogaol, compounds called gingeroids, which may also help with bloating, belching, and discomfort after meals. [64]