Remove 2001 Remove Drug Development Remove Immunization
article thumbnail

PROTAC development gains momentum, but clinical performance is poor

Pharmaceutical Technology

The first concept for a PROTAC was published in 2001, and recently these protein degraders have gained rapid momentum as a promising novel modality. However, on-target adverse events are also common with BTKis as they inhibit B-cell immune responses, which can result in serious infections.

Dosage 59
article thumbnail

Country focus: China & APAC’s growing medical needs bring opportunities and challenges

pharmaphorum

All these factors will support the growth of in-house R&D-driven pharmaceutical companies and bring more innovative drugs to Asian markets.”. Dr Jay Mei has nearly 30 years of experience in clinical research and development of oncology therapeutics globally. Chemotherapy still accounted for 72.6%

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Top 20 Radiopharma Companies Based on Market Cap

PharmaShots

Nordic is advancing the development of CD37-targeted therapies for hematological cancers and immune diseases. The company is developing PPMX-T002, an anti-cancer drug with an antibody targeting CDH3 connected with a radioisotope yttrium 90 (90Y).

Dosage 56
article thumbnail

Meet the company on a mission to transform research and advance healthcare

Pharmaceutical Technology

On the other hand, a lack of diversity in clinical trial populations, particularly when the disease population is significantly underrepresented, greatly diminishes the quality of data obtained for drug safety and efficacy profiles. This may sound obvious, but it is still a major hurdle in drug development.