article thumbnail

2022 spells change for EU pharmaceutical legislation

European Pharmaceutical Review

Directive 2001/83/EC of the European Parliament and of the Council of 6 November 2001 on the Community code relating to medicinal products for human use. One of the key priorities of the EU’s strategy is to encourage innovation to solve unmet medical needs. Future outlook. Brussels; 2020.

article thumbnail

PROTAC development gains momentum, but clinical performance is poor

Pharmaceutical Technology

The first concept for a PROTAC was published in 2001, and recently these protein degraders have gained rapid momentum as a promising novel modality. This makes early R&D less risky, as many lead compounds are discontinued due to inadequate pharmacokinetic profiles and require excessively high dosages to be pharmaceutically active.

Dosage 59
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

How Myo-inositol Can Improve Hashimoto’s Symptoms

The Thyroid Pharmacist

For example, having people take therapeutic dosages of two nutrients, selenium and myo-inositol , in addition to working to balance their blood sugar, can work wonders at reducing their anxiety and OCD symptoms, as well as reducing their thyroid antibodies and thyroid symptoms. Recommended dosage and precautions. Endokrynol Pol.

article thumbnail

MTHFR, Hashimoto’s and Nutrients

The Thyroid Pharmacist

those who may experience more anxiety and irritability) may benefit from a dosage reduction, in the case that their pathways are moving too quickly. Selected Essential and Toxic Chemical Elements in Hypothyroidism-A Literature Review (2001-2021). Some individuals may feel anxious if they start high-dose methylation support too quickly.

article thumbnail

Brain Fog and Hashimoto’s

The Thyroid Pharmacist

As a reminder, please consult with your practitioner to determine which supplements and dosages are appropriate for you. The usual daily therapeutic dosage of citicoline is 500-2,000 mg, taken daily. Tackling these steps will likely bring improvement — or even complete relief — of brain fog for many of you. Endokrynologia Polska.

article thumbnail

Solutions for Constipation Relief

The Thyroid Pharmacist

Be sure to work with your doctor or practitioner to determine the right supplements and dosages for you. Published January 2001. [49] Vitamin D deficiency is common, and many people supplement with it, but there can be too much of a good thing! ResearchGate. Accessed September 22, 2022. [52]

article thumbnail

Top 20 Radiopharma Companies Based on Market Cap

PharmaShots

Market Cap: $29.30M Founded Year: 2001 Total Employees: ~20 Headquarters: Tokyo, Japan Stock Exchange: TYO Perseus Proteomics is a Japanese biotech company focused on developing antibodies by utilizing antibody technology to provide treatment options to patients worldwide.

Dosage 56